Well, it's personal in that I work in a research lab which uses mice in experiments. I'd hazard to say that these animals are kept in a better state than the majority of pet mice. Our techs (who do the majority of mouse work) are made up of a group of 6 animal lovers, one of whom is a vegetarian (we had 3 veggie techs at one time). If I hadn't thought long and hard about this issue and come to the conclusion that at this point in time, mouse work is unavoidable, I wouldn't be working here.
As mentioned in my comment above, working with live animals is extremely expensive. They cost money to buy (especially if you get specific mutants bred from scratch) and a whole lot of money to house. Although everyone in the lab is working toward a common goal (curing leukemia), not all of them do mouse work. Quite a few just stick to signal transduction/molecular biology in vitro stuff.
I'm unclear as to which comment you feel was opinion and not fact? That mouse models of human diseases and therapies have benefitted mankind as a whole? That seems pretty factual to me.
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As mentioned in my comment above, working with live animals is extremely expensive. They cost money to buy (especially if you get specific mutants bred from scratch) and a whole lot of money to house. Although everyone in the lab is working toward a common goal (curing leukemia), not all of them do mouse work. Quite a few just stick to signal transduction/molecular biology in vitro stuff.
I'm unclear as to which comment you feel was opinion and not fact? That mouse models of human diseases and therapies have benefitted mankind as a whole? That seems pretty factual to me.